number - Shnayim Ve'esrim?

Who knows twenty-two?

Please cite/link your sources, if possible. After about one business day, I will:

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  Upvote all interesting answers.

  
  


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  Accept the best answer.

  
  



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  Go on to the next number.

  
  

Answer

22 blemishes that invalidate an Olah (offering). (Likutei HaGra Shebimedrash Tadshei)